A patient with recurrent gout (>3 attacks/year) and visible tophi should begin long-term therapy with:

A patient with RA has numbness in the fingers with positive Tinel and Phalen signs. This most likely represents:

In the United States, the median household income is approximately ____.

Which patient has the highest risk for developing CKD?

Which patient requires referral to nephrology?

The primary role of the epidermis in wound healing is to

A 62‑year‑old man with long‑standing type 2 diabetes presents with a plantar foot ulcer beneath the first metatarsal head. He reports little pain at the site. Exam reveals callus formation around the ulcer, diminished protective sensation to monofilament testing, and intact peripheral pulses. There is no evidence of infection or ischemia. Which intervention is most important to prevent recurrence and promote healing of this type of ulcer?

The recommended cornerstone first-line DMARD for most patients with newly diagnosed rheumatoid arthritis is

A 67‑year‑old man presents with a 2‑year history of gradually worsening motor symptoms. His wife reports that he has become noticeably slower when walking, takes longer to rise from a chair, and has difficulty initiating movements such as buttoning his shirt. On exam, his movements are slow and reduced in amplitude. He has a mild resting tremor in his right hand and cogwheel rigidity at the wrist. Which of the following clinical findings best represents one of the core motor features of Parkinson disease as described by the TRAP mnemonic?

A 34‑year‑old woman presents with intermittent double vision and drooping of her eyelids that worsen toward the end of the day. She reports difficulty chewing and speaking after prolonged talking, but notes that her symptoms improve after resting. Physical examination reveals bilateral ptosis and proximal muscle weakness that worsens with repeated testing. Sensation and reflexes are normal. Which diagnosis best explains this patient’s symptoms?