Scenario E: Carrier screening and test interpretationA PCR-b…
Scenario E: Carrier screening and test interpretationA PCR-based screening test has sensitivity 98% and specificity 99%. In this region, 4% of people are carriers. Assume 1,000 people are tested. Expected outcomes: True carriers: 40 -> true positives 39; false negatives 1 True non-carriers: 960 -> true negatives 950; false positives 10E6. Reasonable next step after a positive screening result:
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