In germinal centers, proliferating B cells undergo a process called somatic hypermutation, in which mutations are introduced into the V regions of the antibody heavy and light chain genes. When this process is complete after several weeks, the overall affinities of the antibodies produced are greatly 

 Effector memory cells (TEM), are recirculating cells that can readily enter tissues at sites of inflammation and are ready to rapidly respond to re-infection. The subset of TEM cells provides an important component of protective immunity to re-infection by the same pathogen because:

Which of the following is a characteristic of mature plasma cells?

Antibody Dependent Cell Mediated Cytotoxicity (ADCC) is

Which of the followoing isotypes can cross the placenta?

While innate immune responses to all types of infections induce local inflammatory responses due to activation of blood vessel endothelial cells, some components of the innate response differ depending on the nature of the pathogen. In the case of intracellular bacterial, dendritic cells and macrophages produce a cytokine that stimulates ILC cells to produce:

What is the role of the FcRn receptor?

 IgA is produced in copious amounts, estimated to be a rate of 3 g/day. Nearly all of the IgA secreting plasma cells are found in the gastrointestinal tract where the secreted IgA is transported across the intestinal epithelium with the help of:

135. One of the organs of the reproductive system is a mucous layer, which forms the placenta during pregnancy. This organ is called the:  

65. An important function of the P.T. when caring for the terminally ill person is to provide: