BCH4024 072425 OC Su25 E3 Q2: A 4-year-old boy is evaluated…
BCH4024 072425 OC Su25 E3 Q2: A 4-year-old boy is evaluated for developmental delay, aggressive behavior, and self-injurious actions such as biting his lips and fingers. His parents report that he has also had episodes of joint swelling and reddish-orange crystals in his diaper. Laboratory tests reveal markedly elevated serum uric acid levels. Genetic testing confirms a diagnosis of Lesch-Nyhan syndrome. Which of the following enzyme is most directly impaired in this patient?
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