A 63-year-old male presents with extreme fatigue and feeling…
A 63-year-old male presents with extreme fatigue and feelings of malaise. A complete blood count reveals a white blood cell count of 83,000 x109 /L, marked anemia and thromocytopenia. A bone marrow aspirate revealed hypercellular marrow with 36% blasts. Immunophenotyping is positive for CD13 and CD33, and negative for CD 19, CD20, CD41 and CD61. Karyotypic yeilds t(8;21) and RUNX1-RUNX1T1 fusion is detected. What is the most likely disorder?
Read DetailsThe CBC for a patient shows decreased WBC and RBC values. Ab…
The CBC for a patient shows decreased WBC and RBC values. Abnormal development is noted for a number of cells on the peripheral blood smear. A bone marrow is ordered and provides the following results: Cellularity is decreased, considering the age of the patient Normal M:E ratio Dysplastic changes noted in myelocytic and erythrocytic cell lines. 17% blasts; Auer rods present
Read DetailsA 25-year-old woman presents with fatigue and pallor. Her la…
A 25-year-old woman presents with fatigue and pallor. Her laboratory results are as follows: Hemoglobin (Hgb): 8.0 g/dL Hematocrit (Hct): 24% Reticulocyte Count: 5% RBC Count: 2.8 x 10⁶/µL Reticulocyte Maturation Factor: 2.0 (adjusted for anemia, for Hct
Read Details