Drug Q has a V of 2.0 L/kg. What loading dose (mg) (i.v. bolus) is required to rapidly attain a Cp of 15 mg/liter? 

The elimination rate constant (KE) can be calculated from

For a particular drug, in a patient with liver disease the FFP went up and the hepatic clearance went down as compared to healthy patients. What is the most likely cause of this observation?

Which of the following does not involve pharmacokinetics?

How would you like another five points?

Which molecule is most likely to get filtered through the glomerular basement membrane?

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A researcher has gathered concentration verses time data for a new drug. Her first data point is obtained 2 hours after i.v. bolus administration of the drug and she decides to use this value to calculate the volume of distribution.  Based on this information:

A researcher has gathered concentration verses time data for a new drug. Her first data point is obtained 2 hours after i.v. bolus administration of the drug and she decides to use this value to calculate the volume of distribution.  Based on this information:

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