Refer to the image above that shows tissue from the pleura of the thoracic cavity with the pleural surface (the aspect closest to the lungs) shown at the top.  Assume H&E stain. What type of tissue layer is the structure indicated by A contained within?

A 45-year-old man presented with a complaint of an increasingly persistent cough that produced moderately thick, white mucus. The patient stated that the cough had been present for several years and was particularly severe in the morning on awakening. His wife was more bothered by the cough than he was and had sent him to the physician so that he might be convinced to stop smoking. On questioning, the patient, who was about 30 lb overweight and had been smoking two packs of cigarettes per day for 20 years, had no other ailments.  Laboratory blood analysis revealed elevated red blood cell counts but normal white blood cell counts, and low blood oxygen but elevated CO2 levels. For this question, refer to the case study and framework, provided above, as needed.  Identify two clinical manifestations (signs and symptoms) of disease for the patient.

Monocytes can migrate out of blood into a tissue where they will differentiate into…

If you examined a tissue and observed that the cytoplasm in a few cells stained especially deeply by eosin, what might this tell you about those cells?

In recent years, the most common cause of death in the U.S. has been due to disease associated with this organ.

What is one feature of neutrophils that allows them to be distinguished from monocytes using light microscopy?

Hematoxylin (haematoxylin) is a natural dye extracted from the heartwood of the Logwood tree.  When oxidized and complexed with metal ions (as is the case with H&E), it can be used to stain this cellular structure most intensely.

In the liver, the primary parenchymal cell is the…

Cell injury is sometimes irreversible meaning that…

Compared to almost all other organs in the body, the liver experiences a different blood flow pattern.  Explain the major difference.