A 25-year-old female with a history of recurrent deep vein thrombosis is found to have a mutation in factor V Leiden.  What is the primary mechanism by which this mutation increases the risk of thrombosis? 

Which part of the shoulder joint is often affected by degenerative diseases? 

A 60-year-old male is diagnosed with lung cancer. Genetic testing reveals a mutation in the EGFR gene, a proto-oncogene, leading to its activation as an oncogene.  What is the primary effect of this mutation on the cell? 

An 80-year-old woman sustains a hip fracture after a minor fall. Which underlying condition is most likely responsible? 

What is the primary role of chemotactic factors in acute inflammation? 

What is the primary function of osteocytes in bone tissue? 

A patient with cancer is undergoing immunotherapy to enhance the activity of their T cells. How are these T cells typically activated? 

Which of the following conditions is more common in older adults due to hypercoagulability? 

What occurs during the herniation of an intervertebral disc? 

What major event occurs during the S phase of the cell cycle?