In a 1 month old with alpha thalassemia, you would expect to find:

What is the MCHC in grams per deciliter (g/dL)?

In hemoglobin C disease, how does the mutation affect the hemoglobin molecule?

A patient has the following CBC values WBC = 10.2 x 109/L RBC = 5.5 x 1012/L HGB = 11.3 g/dL HCT = 35.3 L/L MCH = 20 pg MCHC = 32.0 g/dL MCV = 64 fL PLTS = 222 x 109/L Using this data, calculate and interpret the mentzer index:    

A 25-year-old woman presents with fatigue and pallor. Her laboratory results are as follows: Hemoglobin (Hgb): 8.0 g/dL Hematocrit (Hct): 24% Reticulocyte Count: 5% RBC Count: 2.8 x 10⁶/µL Reticulocyte Maturation Factor: 2.0 (adjusted for anemia, for Hct

A patient’s hemoglobin electrophoresis on cellulose acetate shows a prominent band in the position of Hemoglobin S. However, the sickle solubility test is negative (image, middle). What is the most appropriate next step to confirm the identity of the hemoglobin variant?    

A 62-year-old patient presents with complaints of fatigue, pallor, and occasional shortness of breath. On examination, he has pale conjunctiva and mild glossitis. A CBC reveals the following results: Hemoglobin: 8.5 g/dL  MCV: 115 fL WBC: 3.2 x 10⁹/L  Platelets: 95 x 10⁹/L  Reflex Tests Ordered: Serum Vitamin B12: Low Serum Folate: Normal Serum Iron: Normal Bone Marrow Biopsy: Hypercellular with dysplasia in all three cell lines. Based on the clinical findings and laboratory results, which is the most likely diagnosis, and what features differentiate this diagnosis?    

Evaluate the hematology data and identify the most likely diagnosis: WBC Count: 12.5 x 10⁹/L RBC Count: 4.6 x 10⁶/µL Hemoglobin (Hgb): 13.8 g/dL Hematocrit (Hct): 41% Platelet Count: 180 x 10⁹/L Differential Count: Neutrophils: 35% Lymphocytes: 50% Monocytes: 10% Eosinophils: 3% Basophils: 2%  

A patient’s RBC morphology appears as shown in the image below. Which is the most appropriate initial test to distinguish the cause of this disorder?

Evaluate the images of scatterplots from the Sysmex-XN. Match each diagnosis with the corresponding scatterplot image.