37.    Patient LH (male, 90 years old, weight 57 kg) is a nursing home resident with frailty. He has a long-term indwelling urinary catheter in situ due to benign prostatic hyperplasia causing bladder outlet obstruction. This was last changed 3 days ago. He currently takes only paracetamol 1 g when required four times daily and has no known drug allergies. Today he is unwell with lethargy, confusion, nausea, flank pain and a temperature of 38.2°C.Which initial management option is MOST APPROPRIATE?

23.    Patient GO (male, 33 years old, height 180 cm, weight 80 kg) has presented to Accident and Emergency following a paracetamol overdose. He has been started on an acetylcysteine infusion and has begun to feel unwell; he complains of difficulty breathing and he has developed a wheeze.Which management option would be the MOST APPROPRIATE for Patient GO?

28.    Patient LK (female, 55 years old, 50 kg) has been diagnosed with a deep vein thrombosis (DVT).Past medical history:•    Lumbar spinal stenosis•    Hypertension•    Chronic kidney diseaseMedication history:•    Co-codamol 8/500 mg takes 1-2 four times daily (buys over the counter)•    Lisinopril 40 mg once daily•    Dapagliflozin 10 mg once daily•    Epoetin alfa dose adjusted by renal specialist nurseBlood results: eGFR 40 ml/min/1.73m2, serum creatinine 60 micromol/L (60 – 100), prothrombin time (PT) 12.0 s (11.5 – 15.5), activated partial thromboplastin time (aPTT) 35 s (30 – 40).Which statement is CORRECT?

39.    Patient AG (male, 23 years old, weight 82 kg) is known to have asthma; he has no other medical conditions. His regular medications are:•    Salbutamol pressurised metered dose inhaler 100 micrograms/puff 2 puffs when required•    Beclometasone (Clenil) 200 micrograms/puff 2 puffs twice dailyHis recorded best PEFR is 490 L/min.He has had a bad cold over the last few days and began to feel increasingly wheezy and short of breath. Today he feels extremely breathless and is struggling to complete sentences. His current PEFR is 240 L/min, respiratory rate is 28 breaths per minute, heart rate 110 beats per minute.Based on this information, pending further investigations and examinations, which statement is CORRECT?

8.    Patient CL (female, 44 years old, weight 63 kg) has been admitted to the surgical ward with acute abdominal pain and diagnosed with suspected appendicitis. She is nil by mouth prior to an appendectomy. Her current pain score is 9/10.Past medical history:•    AsthmaMedication history:•    DuoResp Spiromax® 320 micrograms/ 9 micrograms one puff twice dailyWhich approach to pain management is MOST APPROPRIATE?

Biodiversity in an ecosystem can be measured by the number of and the relative abundance of each species in the community

Catalase is an enzyme that converts the substrate into the products and .

What does EOQ stand for in inventory management?

Inventory cost includes all of the following EXCEPT:

A markdown is: