A bone marrow specimen is received in the cytogenetics lab. …
A bone marrow specimen is received in the cytogenetics lab. FISH analysis has been ordered. The MLS performs the assay and notices that 96% of the patient’s cells contain both 5q– and 7q– deletions. These cytogenetic findings are characteristic of:
Read Details60-year-old patient visited his general practitioner because…
60-year-old patient visited his general practitioner because of fatigue and unexplained bruising. Physical examination revealed a frail, thin, pale man with widespread bruising. A CBC was ordered and revealed abnormal granularity of platelets and leukocytes. Red cells appeared dimorphic. Bone marrow analysis showed 20% ringed sideroblasts with dysplastic changes in RBC and WBC precursors. No cytogenetic abnormalities were detected. Based on this information, what is a probable diagnosis?
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