A 35-year-old female presents with butterfly-shaped facial rash, joint pain, and fatigue. Labs show a positive ANA and anti-dsDNA antibodies. What is the most likely diagnosis?

A patient presents with chest pain that began 20 minutes ago. ECG shows ST elevation in leads II, III, and aVF. Which cardiac marker would rise first?

A 72-year-old male presents with anemia and weight loss. Colonoscopy shows a mass in the ascending colon. What symptom is most commonly associated with this type of colon cancer?

A 64-year-old male with long-standing alcohol use disorder is found confused and unable to recall recent events. He fills memory gaps with made-up stories. What is the most likely cognitive phenomenon?

A 75-year-old woman reports severe morning jaw pain and scalp tenderness. ESR is markedly elevated. What serious complication should be screened for?

A 58-year-old man experiences excruciating unilateral orbital pain with lacrimation and nasal congestion lasting 30 minutes. What is the most likely diagnosis?

A 68-year-old male has worsening dyspnea and is found to have a pleural effusion. The fluid is exudative and shows malignant cells. What is the most likely underlying cause?

A 50-year-old female with chronic fatigue and pallor is found to have macrocytic anemia. She also has glossitis and peripheral neuropathy. What is the likely cause?

A patient with uncontrolled hypertension develops chest pain radiating to the back. CT shows a widened mediastinum. What is the most likely diagnosis?

A patient with active tuberculosis presents with hemoptysis, night sweats, and weight loss. What test confirms the diagnosis?