Resistance to oseltamivir occurs by the following mechanism: (1)1.       Point mutations in the cytochrome b gene2.       Mutations on the enzyme catalase-peroxidase3.       Mutations in the neuraminidase enzyme 4.       Mutations in the target enzymes L-alanine racemase and D-alanine ligase5.       Mutations in the glucan synthase enzyme

The following drugs is a methylxanthine derivative: (1)1.       Salmeterol2.       Fluticasone3.       Ciclesonide4.       Loratadine5.       Aminophylline

Timolol: (1)1.      Causes mydriasis 2.      Is used in the management of glaucoma3.      Can be used to treat chronic obstructive pulmonary disease4.      Reverses non-depolarizing neuromuscular block5.      Is used in the treatment of myasthenia gravis

The following is classified as a thiazide diuretic: (1)1.       Spironolactone2.       Hydrochlorothiazide3.       Chlortalidone4.       Acetazolamide5.       Bumetanide

Match the following drugs with their appropriate statements below. Each drug may be used more than once or not at all: (5)

The following are used in the treatment of rheumatoid arthritis except: (1)1.       Etanercept2.       Sulfasalazine3.       Rituximab4.       Methotrexate5.       Indacaterol

The following drug is classified as a H2-receptor antagonist: (1)1.       Promethazine2.       Infliximab3.       Metoclopramide4.       Pantoprazole5.       Ranitidine

The following drug acts by blocking dopamine receptors in the chemoreceptor trigger zone: (1)1.       Lactulose2.       Ondansetron3.       Aprepitant4.       Prochlorperazine5.       Granisetron

The following is not appropriate for management of uncomplicated acute bacterial sinusitis: (1)1.       Humidifier 2.       Saline irrigation3.       Intranasal steroid spray4.       Oral antibiotics5.       Intravenous antibiotics

The following is an advantage of the sublingual route of drug administration: (1)Slow absorptionCan be used in unconscious patientsExhibits the highest bioavailabilityOverdose can be treated with antidotes such as activated charcoalAvoidance of first-pass metabolism