Nguyen – Autoimmunity Systemic Lupus Erythematosus (SLE), co…
Nguyen – Autoimmunity Systemic Lupus Erythematosus (SLE), commonly known as lupus, is a chronic autoimmune disease characterized by the body’s immune system attacking its own tissues and organs. This results in widespread inflammation and tissue damage in affected organs, including the skin, joints, kidneys, brain, and other parts of the body. Recent observations have suggested a potential association between SARS-CoV-2 infection and the onset or exacerbation of lupus in certain individuals. One hypothesis for this association is molecular mimicry. Design detailed experiments to investigate whether molecular mimicry is the principal mechanism by which SARS-CoV-2 infection leads to the development of lupus. Your experimental framework should include plans for both mouse models and human subjects.
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