All known DNA polymerases catalyze synthesis only in the 5’…
All known DNA polymerases catalyze synthesis only in the 5′ –> 3′ direction. Nevertheless, during semiconservative DNA replication in the cell, they are able to catalyze the synthesis of both daughter chains, which would appear to require synthesis in the 3′ –> 5′ direction. Explain the process that occurs in the cell that allows for synthesis of both daughter chains by DNA polymerase.
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