In the brainstem, which controls reflexes such as vomiting, the extracellular signal Substance P binds to a GPCR and triggers vomiting. In an attempt to prevent chemotherapy-induced vomiting, a new drug called Rolapitant has been developed. How can Rolapitant prevent vomiting?

Which of the following proteins adds inhibitory phosphates to the ATP-binding site in CDK1?

Many rainforest plants have potential anti-cancer properties. One such plant, P. cupana, was used to treat cancer in mice. After treatment, tumor growth was inhibited, and the cancer cells had decreased expression of cyclin D. What checkpoint of the cell cycle did the cells stop at based on this evidence?

In most resting eukaryotic cells, the concentration of intracellular Ca2+ is usually kept at least ______ times ______ than the extracellular concentration.

As soon as cohesin is cleaved:

Pick all the statements below that apply to microtubules.  Warning: you will lose points for selecting choices that are not correct.  

Autocrine signaling is a type of:

Dyneins are ______ than kinesins and walk towards the ______ end of microtubules.

The image below shows steps in a phosphorylation cascade (1-5).  Match the proteins (A-E) from the box on the right to the correct steps in the cascade figure below to the left:   Step 1[1],   2 [2],   3 [3],   4 [4],   5 [5].  Just use the uppercase letter (and not the name of the enzyme) to fill in the blanks.

Which of the following extracellular signals binds to intracellular receptors?