To reduce the thermal stability of his globular protein, Mr….
To reduce the thermal stability of his globular protein, Mr. Dolittle decides to introduce mutations in the hydrophobic core of the protein. For this he needs to know the 3D structure of his protein. So he searches all protein structure databases but does not find any 3D structures. And so he gives up! What would you do in his place — provide a brief outline of your strategy to obtain a 3D structural model of his protein.
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