A mutation in the hemoglobin protein causes sickle-cell anem…
A mutation in the hemoglobin protein causes sickle-cell anemia, which can be fatal if both alleles are affected. However, the allele for sickle-cell anemia provides a natural resistance to malaria. Homozygotes either get malaria (if they have two normal alleles) or are resistant to malaria but can die from sickle-cell anemia (if they have two sickle-cell alleles). Heterozygotes only deal with minor effects of sickle-cell and have a high chance of malaria resistance. Which of the following would likely occur in populations where malaria is common?
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