The following is the mechanism of action of mebendazole:                                          1.        It inhibits parasitic mitochondrial phosphorylation of adenosine diphosphate                                                                                                                                                   2.        It diminishes the energy production of the nematode                                                                                                                                                                                     3.        Causes death of parasites by increasing the permeability of the cell membrane to calcium ions                                                                                                                        4.        Enhances chloride influx leading to hyperpolarization, resulting in death of worm     5.        It is converted to hydrogen sulfide, which has a lethal action on the ectoparasite    

Folic acid may decrease the efficacy of the following agent during toxoplasmosis  treatment:                                                                                                                           1.        Azithromycin2.        Folinic acid3.        Clindamycin4.        Pyrimethamine5.        Suramin

The following drug is indicated for the treatment of cytomegalovirus:                                                   1.        Lamivudine2.        Oseltamivir 3.        Ribavirin4.        Ganciclovir5.        Darunavir

HIV post exposure prophylaxis for occupational exposures may not be administered:                                                                                                                                                                              1.                           For exposures to fluids that contain blood2.                           If the source patient is HIV-seronegative, with features suggestive of a seroconversion illness3.                           If the healthcare worker is HIV-infected4.                           If the health care worker is not HIV-infected5.                           If the health care worker consents to HIV post-exposure prophylaxis

Concomitant use of the following drug with sildenafil is potentially fatal:                  1.        Lamivudine2.        Lidocaine3.        Isosorbide mononitrate4.        Omeprazole 5.        Tenofovir

Match the following drugs with the relevant adverse effects. Each drug may be used more than once or not at all:

 The following drug is a benzimidazole derivative:                                      1.        Mebendazole2.        Metronidazole3.        Niclosamide4.        Sulfiram5.        Dimeticone 

The following is the mechanism of action of proguanil:                                                            1.        It inhibits the detoxification of the heme in the erythrocyte2.        Its metabolites produce reactive oxygen species which are fatal to the malaria parasite3.        Its metabolites inhibit nucleic acid synthesis by oxidizing plasmodial DNA4.Inhibits plasmodial protein synthesis by binding to 30S ribosomal subunits5.        It inhibits plasmodial dihydrofolate reductase enzyme action

 An 8 month old is having a “tet spell” while blood is being drawn.  The nurse’s first action  should be which of the following?

        A baby is evaluated, a VSD(Ventricular Septal Defect) is diagnosed.  How would you explain this cardiac defect to the parents when they ask you about it?