If a mutant sigma factor binds very tightly to RNA polymerase, how might that affect transcription?

  Epigenetic changes may  

Which of the following phenomena could you study using ChIp-Seq?

The Avy allele of the Agouti gene involves the insertion of a transposable element upstream from the normal Agouti promoter. Let’s suppose that pregnant female mice are fed a diet that contains chemicals that increase DNA methylation. With regard to offspring carrying the Avy allele, this diet would

A gene encodes a pre-mRNA with 5 exons and 4 introns.  A mutation eliminates the 3’ splice site from intron 3. What exons would be found in the mRNA after splicing was completed?

You ARE allowed to use a calculator and scratch paper and handwritten notes.  By typing your name in the box below, you are pledging to follow these rules and you are pledging NOT to discuss the questions or answers with anyone else until after the exam key has been posted, which is usually a few days after the exam deadline.  Note: It is not possible to create an answer key that gives your particular name as the correct answer. Therefore, the answer key will say that you got this question incorrect. Don’t worry about that issue because this question is worth zero points.

Which of following types of genetic sequences would come first in a gene?

For a riboswitch that controls translation, the binding of a small molecule such as TPP controls whether the RNA

A mutagen that alkylates bases is

The role of sigma factor during bacterial transcription is to cause