A rose gardener pricked themselves with a contaminated thorn. A subcutaneous fungal infection characterized by necrotic lesions followed this direct inoculation of fungal spores into the skin. The most likely agent causing the infection is:
Read DetailsA previously healthy, immunocompetent 35-year-old patient living in Ohio presented to the emergency room with a chronic cough. In addition to the cough, they had several painless subcutaneous nodules. They had no travel history outside of Ohio. Microscopic examination of the tissue showed broad-based budding yeast. The most likely agent causing the infection is:
Read DetailsOpportunistic mycoses have increased significantly over the last 3 decades. This has created a challenge to both the laboratorian and the physician in the determination of the clinical significance upon isolation of opportunistic fungi in clinical specimens. 1. List 4 different/diverse factors that have led to the increase in opportunistic mycoses. (4 pts) 2. Which of the discussed opportunistic fungi creates the most challenges in healthcare today? Explain your choice. (3 pts)
Read DetailsModes of action for antifungal agents include: inhibitors of cell walls/cell membranes, and protein and nucleic acid synthesis; and direct membrane damage. Which of the following is a mismatch between the antifungal agent and its mode of action?
Read DetailsA 58-year-old patient was taken to surgery for debridement of the left sinus. Direct smear of the clinical material from the left sinus obtained at the time of surgery indicated the presence of a mucormycete (zygomycete). Which of the following factor(s) predisposes an individual to infection caused by the group of fungi? Select all that apply.
Read Details