The following is the mechanism of action of mebendazole: …
The following is the mechanism of action of mebendazole: 1. It inhibits parasitic mitochondrial phosphorylation of adenosine diphosphate 2. It diminishes the energy production of the nematode 3. Causes death of parasites by increasing the permeability of the cell membrane to calcium ions 4. Enhances chloride influx leading to hyperpolarization, resulting in death of worm 5. It is converted to hydrogen sulfide, which has a lethal action on the ectoparasite
Read DetailsHIV post exposure prophylaxis for occupational exposures may…
HIV post exposure prophylaxis for occupational exposures may not be administered: 1. For exposures to fluids that contain blood2. If the source patient is HIV-seronegative, with features suggestive of a seroconversion illness3. If the healthcare worker is HIV-infected4. If the health care worker is not HIV-infected5. If the health care worker consents to HIV post-exposure prophylaxis
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