Directions: Calculate the following dosage. Use a leading zero if it applies. Do not use a trailing zero.    Order:  Administer Rocephin 250 mg IM. Available:  Rocephin 1 g.  To reconstitute, add 3.6 mL of sterile saline and agitate gently to completely dissolve powder.  The reconstitution provides a total volume of 4 mL.How many mL will the nurse administer?

Directions: Calculate the following dosage. Round the answer to the tenth.  Order: Ativan 3.5 mg IM Available:How many mL will the nurse administer?

Directions:  Calculate the fluid volume for this client.   Ordered: D5 NS is infusing at 28 drops/min. The drop factor is 10 drops/mL. How much fluid volume in mL will the client receive in 8 hr?

Directions: Calculate the number of mg needed for the nurse to administer. Round answer to a whole number if it applies. Order:  A nurse is caring for an adolescent client who has pneumonia and a prescription for cefpodoxime 5 mg/kg PO every 12 hr. The client weighs 88 lb.How many mg should the nurse administer per dose?

Directions: Calculate the following dosage. Round answer to the tenth. Order: Zofran 7 mg p.o. Available: Zofran oral solution labeled 4 mg per 5 mL.How many mL will the nurse administer?

Directions: Calculate the following dosage.  Round answer to the tenth. Order: Clindamycin 0.475 g IM Available:How many mL will the nurse administer?

Directions: Calculate the following dosage. Round answer to the tenth.  Use a leading zero if it applies.  Do not use a trailing zero.Order: Heparin 2,000 units subcutaneous dailyAvailable:How many mL will the nurse administer?

(10 pts) In the journal club this module what type of particles were used to deliver the mRNA. What was the goal of the paper and reference one of the figures from the journal club to help prove your answer? Can you describe one other disease that could benefit from this approach? Reference one of the figures from the journal club to help prove your answer.

Properties that limit adsorption of small molecules Size Structure State Hydrogen Bonding Potential All of the above Which drug delivery method has the shortest duration for onset of action: sublingual Intramuscular ingestion Intravenous transdermal 3.  Which cell/cell junction is primarily responsible for limiting passage of molecules (drugs) between cells? Desmosomes Tight Junctions Adherens Junctions Gap Junctions None of the above

(10 pts) Name the 3 barriers discussed in class. The intestinal mucosal epithelium presents _______ barrier (name the barrier type) to drug delivery. Describe one method (transcellular or paracellular) in which a drug molecule may pass this barrier. What are 2 advantages and disadvantages of this route of delivery?