Which of the following statements best describes the affinity of a drug?

RULE OF 3s and 5s… Consider the antihistamine drugs Loratadine (Claritin®) and Desloratadine (Clarinex®). Recall Lipinski’s Rule of 5 and answer the following questions… *** a) Does DESLORATADINE meet the requirements for hydrogen bond donor capability?   How many HBD groups are present? [blank1]       *** b) Does DESLORATADINE meet the requirement for hydrogen bond acceptor capability? How many HBA groups are present? [blank2]         *** c) Is the in vivo metabolic conversion of loratadine to desloratadine a Phase I or II rxn? [blank3] *** d) Using the “RULE OF 3s”, complete the table below to predict whether the logP values for the drug DESLORATADINE would be less than, greater than, or equal to 0.     Carbon# =  [blank4] Water# = [blank5] Log P   [blank6]  0  

Given the following log P values, what is the predicted log P value for the disubstituted structure?  

logP questions

From July through December, Community Hospital had 32 patients with complications and 2,394 discharges.  Calculate the complication rate.  Round to two decimal places. 

An HIM manager must determine the number of FTEs needed to code 950 discharges per week. It takes 20 minutes to code each record. Each coding professional works 37.5 productive hours per week. How many FTEs will the HIM manager need? Round to one decimal place.

What is the calculation formula for Gross Mortality Rate?

Community Hospital reported the following statistics for the month of February.  What is the Fetal Mortality Rate?  Round your answer to two decimals places. Live births 37 Newborn discharges and deaths 36   Fetal Deaths      Early 1      Intermediate 4      Late 3

What is the calculation formula for Rate

What is the calculation formula for Maternal Mortality Rate?