State two complications of antimicrobial therapy.

Match the following drugs with the most corresponding adverse effect below. Each answer may be used more than once or not at all.        

Amoebiasis therapy includes the following:                                                                      1.        Tenofovir2.        Niacin3.        Metronidazole4.        Isoniazid5.        Lamivudine  

Name the antidotes of the following conditions: Opioid overdose           Malignant hyperthermia                                                                                                             Benzodiazepine overdose    

Regarding fluoroquinolones:                                                                                                  1.       Are hepatically metabolised2.       Are bacteriostatic3.        Are bactericidal4.        Are renally excreted5.        Increase the metabolism of warfarin   

Match the following drugs with the appropriate mechanism of action below. Each answer may be used more than once or not at all.   

Describe the mechanism of action of lamivudine.                                                                   

The following are classified as Non-steroidal anti-inflammatory drugs (NSAIDs) except:                                                                                                                                                                      1.        Ibuprofen2.        Paracetamol3.        Aspirin4.        Diclofenac5,        Indomethacin 

Describe the mechanism of action of dolutegravir.                    

Regarding drug interactions with penicillins:                                                                      1.       Administration with erythromycin inhibits penicillins’ effects2.       Administration with streptomycin has synergistic effect with penicillins3.       Administration with salicylates inhibits penicillins’ effects4.       Administration with probenecid enhances penicillins’ effects5.       Administration with tetracycline enhances penicillins’ effects