Here is the sequence around the translation initiation codon…
Here is the sequence around the translation initiation codon (AUG) of a human mRNA: 5’—-AAGGGAUGGAACCUAGC….—-3’ You have isolated a mutant version of the gene encoding this mRNA that contains a frameshift mutation. A one base pair insertion (base pair is underlined) occurs after the start codon (AUG). This change generates the mRNA shown below: 5’—-AAGGGAUGGAAACCUAGC….—-3’ This mutation will cause a premature stop in:
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