An investigator conducts a study comparing lowopril (a new A…
An investigator conducts a study comparing lowopril (a new ACE-inhibitor) to lisinopril in patients with uncontrolled hypertension. The NI margin is set at 6 mmHg. Lowopril lowered blood pressure by 6.1 mmHg and lisinopril lowered by 7.8 mmHg. The difference in blood pressure lowering was 1.7 mmHg (95%CI -0.1 to 3.5). Describe the appropriate interpretation of the results in the context of the NI margin.
Read DetailsAn investigator would like to determine the impact of dietar…
An investigator would like to determine the impact of dietary vitamin D on the incidence of bone fracture among children ages 8-10 years. Which of the following study designs would be best for reducing the likelihood of recall bias?
Read DetailsA RCT was conducted to test the efficacy of a new failure he…
A RCT was conducted to test the efficacy of a new failure heart medication compared to placebo to prevent major adverse cardiac events (MACE). The new medication was found to decrease MACE compared to placebo (RR 0.74; 95%CI 0.46 to 1.02). How is this best interpreted?
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