Indicate whether the following statements are true or false.  [answer1] Reovirus enters into the target cell by first being captured as a “cargo” into a endocytic vesicle. [answer2] Reovirus is activated when an outer shell viral protein is attacked by an intestinal protease. [answer3] The nuclear envelop is thought to have evolved by invagination and pinching off from the plasma membrane of an ancient archaeon. [answer4] An antibiotic that inhibits protein synthesis of a bacterium will likely inhibit protein synthesis in mitochondria. [answer5] Most mitochondrial proteins are made within mitochondria.  [answer6] The electrical potential of a charged molecule is zero if the membrane potential is zero.

Indicate for each of the following statements whether it is likely to be true or false.  [answer1] The mannose-6-phosphate tag on the oligosaccharide chain marks a lysosomal enzyme for delivery to the lysosome.  [answer2] The low pH in the lysosomal lumen facilitates the unloading of the lysosomal enzymes from the M6P receptor. [answer3] ER is involved in glycosylating proteins to be delivered to the lysosome.

You have discovered a drug that blocks the ability of Ran to hydrolyze GTP.  When you apply this drug to a cell, what is the likely effect on nuclear import?

A provider has ordered a blood product transfusion for a postoperative patient. The nurse reviews the provider’s order to administer 1 unit of packed red blood cells containing 325 mL of blood over 3 hours. Question: What rate (in mL/hr) does the nurse set the IV pump to administer the blood product within this timeframe? Round to the nearest whole number. Enter numeric value only. 

A patient requires IV fluids, and the physician orders 1000 mL of 0.9% NaCl to be administered over 12 hours. You prepare your tubing and obtain an IV pump. Question: What will the flow rate be in mL/hr? Round to the nearest whole number. Enter numeric value only.

A patient is prescribed 200 mg of Lisinopril to be administered orally. The Lisinopril tablets available are 50 mg each. Question: How many tablets of Lisinopril should be administered to the patient to provide the correct dosage? Enter numeric value only. 

A patient requires an intravenous infusion of 500 mL of fluid over 4 hours. The infusion set has a drop factor of 20 gtt/mL. What is the correct drip rate in gtt/min? Round to the nearest whole number.

The nurse is monitoring the 24-hour fluid balance in a patient with renal disease. The nurse must calculate the total 24-hour intake of intravenous fluids. The patient has the two following intravenous orders: 1) continuous 0.9% NaCl at 65 mL/hr, and 2) Ancef (cefazolin) 1 g IV Q6H. The Ancef (cefazolin) is supplied as 1 g in 50 mL of 0.9% NaCl per dose. Question: Based on the orders indicated, what is the total volume in mL of intravenous fluids that this patient is expected to receive within a 24-hour timeframe? 

The provider orders 2L of 0.9% NaCl to be delivered at 125 mL/hr. Question: How much time (in hours) will it take to complete the infusion as ordered? Round to the nearest tenth. Enter numeric value only.

Are you using scratch paper? If so, please show it to the camera before answering any questions