There are a variety of data that act as evidence of evolution. We discussed four key pieces of evidence of evolution in class: direct observations, homology, fossils, and biogeography.List the four pieces of evidence of evolution as discussed in class. For each one, provide either a definition or example. You will also need to discuss how each piece of evidence supports the theory of evolution. Each piece of evidence (name, definition/example, support of the theory) is worth 5 points. The definition/example is worth 2 points, and how each piece of evidence supports the theory of evolution is worth 3 points (20 points total).

A mutation in the hemoglobin protein causes sickle-cell anemia, which can be fatal if both alleles are affected. However, the allele for sickle-cell anemia provides a natural resistance to malaria. Homozygotes either get malaria (if they have two normal alleles) or are resistant to malaria but can die from sickle-cell anemia (if they have two sickle-cell alleles). Heterozygotes only deal with minor effects of sickle-cell and have a high chance of malaria resistance. Which of the following would likely occur in populations where malaria is common?

Using the BNF treatment summaries, what does it state about associated health benefits in relation to the combined hormonal contraceptives?

What is the dose of oral phenoxymethylpenicillin for an acute sore throat in adults?

20.  What interaction occurs and what is the severity if bemiparin is prescribed with aceclofenac or if prescribed with escitalopram? 

What is the definition for bioavailability? 

What does the BNF state in regard to further information for side effects related to dapagliflozin? 

23.  What is midazolam unlicensed for in adults and in children? 

What is the cautionary label number and what does the cautionary label state in relation to aripiprazole ?

What is budesonide unlicensed for in children?