The following is the mechanism of action of proguanil:                                                            1.        It inhibits the detoxification of the heme in the erythrocyte2.        Its metabolites produce reactive oxygen species which are fatal to the malaria parasite3.        Its metabolites inhibit nucleic acid synthesis by oxidizing plasmodial DNA4.Inhibits plasmodial protein synthesis by binding to 30S ribosomal subunits5.        It inhibits plasmodial dihydrofolate reductase enzyme action

 An 8 month old is having a “tet spell” while blood is being drawn.  The nurse’s first action  should be which of the following?

        A baby is evaluated, a VSD(Ventricular Septal Defect) is diagnosed.  How would you explain this cardiac defect to the parents when they ask you about it?

A child is admitted to the pediatric unit with increased secretions, cough, and  nasal drainage.  Physician diagnoses the child with RSV.   A priority nursing diagnosis would be:

You are working with a family with and a child who has a congenital heart defect.  Future surgery is planned and you are teaching the parent how to reduce cardiac demands.  The parent needs more teaching when she says  which of the following?

Parents bring a toddler who is 2.5 years old to the hospital because of observed difficulty in breathing. In addition, they share at bedtime the toddler has a barky cough. The toddler is diagnosed with laryngotracheobronchitis. Which assessment does the nurse expect to find with this diagnosis? 

In epithelial cells of the epidermis, the intermediate filament proteins that attach hemidesmosomes and desmosomes to the cytoplasm are made of__________ which is synthesized on _______________.

Epidermolysis bullosa is an inherited disease where keratinocytes separate from the dermis. You would expect that the mutations which cause this disease to be genes that encode for proteins found in:

A relatively small number of genes appear to account for much of the variation in skin color observed in humans. Two genes that have undergone positive selection in northern latitudes are OCA2 in Asian populations and SLC24A5 in European populations. In the ancestral African population, the SLC24A5 gene produces a protein with an alanine at amino acid position 111. In the European population the amino acid at position 111 is threonine. The protein that is produced from the SLC24A5 gene exchanges an ion of Na+ from the cell cytoplasm for a Ca2+ ion on the outside of the cell. This exchange appears to be necessary for normal melanin synthesis. In East Asian populations, the OCA2 gene produces a protein with the amino acid arginine at position 618 whereas the ancestral amino acid at that position is histidine. For both genes, the mutation arises from a single base change called a Single Nucleotide Polymorphism The mutations in the SLC24A5 gene affects protein expression in ___________________ while the pigments produced and secreted from these cells are taken up by __________________.

Which of the following would you expect to have no glycosylated amino acids?