The CBC for a patient shows decreased WBC and RBC values. Abnormal development is noted for a number of cells on the peripheral blood smear. A bone marrow is ordered and provides the following results: Cellularity is decreased, considering the age of the patient Normal M:E ratio Dysplastic changes noted in myelocytic and erythrocytic cell lines.  17% blasts; Auer rods present  

Match the MCV/RDW that would most likely correlate with each clinical scenario.

In a 1 month old with alpha thalassemia, you would expect to find:

Hypersegmentation of neutrophilic nuclei is hallmark of which disorder?

A 25-year-old woman presents with fatigue and pallor. Her laboratory results are as follows: Hemoglobin (Hgb): 8.0 g/dL Hematocrit (Hct): 24% Reticulocyte Count: 5% RBC Count: 2.8 x 10⁶/µL Reticulocyte Maturation Factor: 2.0 (adjusted for anemia, for Hct

Combined with the relative reticulocyte count, which index can provide the greatest insight into activity of the bone marrow during treatment for an anemia? 

You are performing a differential for a patient with absolute leukocytosis and lymphocytosis. The following peripheral blood picture under the microscope should prompt you to do which of the following?

Hypersegmentation of neutrophilic nuclei is hallmark of which disorder?

Hypochromic, microcytic anemia is found in which stage of iron deficiency?

A 9-year-old girl has bruising noted on the extremities and back, reportedly recurrent for one month duration. Lab results show a Hgb 7.1 g/dL, Hct 22.8%, MCV 89 fL, platelet count 63,000/µL, WBC count 19,128/µL. BM biopsy shows 100% cellularity with replacement by primitive cells with large nuclei, delicate chromatin; indistinct nucleoli with scanty cytoplasm. These cells mark for CD10 (CALLA) antigen. Which of the following is the most likely diagnosis?