The phenotype of cyclopic lambs reminded scientists studying…
The phenotype of cyclopic lambs reminded scientists studying the loss of function mutants of the _________________ signaling pathway which showed craniofacial abnormalities including cyclopia that they may both be caused due to a similar molecular mechanism. The phenocopy of teratogenic action of Veratrum californicum alkaloids with the above genetic mutant phenotype eventually led scientists to pinpoint the role of cyclopamine albeit with integration of multiple fields.
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