When a leukemia is suspected in a patient, what laboratory test should be required for the initial diagnosis?

A 49-year-old woman was admitted to the hospital for easy bruising and menorrhagia. She had evidence of disseminated intravascular coagulation. Her white blood cell count is 3 x 10^9/L with 95% large, atypical mononuclear cells and some atypical bilobed cells. Many of these cells are packed with larger, purple-staining granules; some have multiple Auer rods; and all are strongly peroxidase-positive. What is the diagnosis?

TdT terminal deoxynucleotidyl transferase is found in 90% of acute __________ leukemia.

The presence of Auer rods in the cytoplasm of cells rules out __________.

Bone marrow aspiration in myelofibrosis frequently results in a __________.

Which X-linked recessive disease is characterized by a granuloma formation as a result of the inability of neutrophils, monocytes, and eosinophils to kill microorganisms after normal engulfment?

A 35-year-old man presents with anemia, neutropenia, thrombocytopenia, myeloblasts with the presence of Auer rods, and one or two distinct nucleoli and promyelocytes. Cytochemistry examination demonstrates peroxidase and Sudan black B (SBB) positive and TdT terminal deoxynucleotidyl transferase (TdT) negative. This hematologic picture is consistent with:

In the hypercellular (prefibrotic) phase of chronic idiopathic myelofibrosis (CIMF), the bone marrow displays panhyperplasia with a predominance of __________.

Gaisböck’s syndrome refers to hypertensive patients who present with increased red cell counts, plethora, and absence of splenomegaly. This relative polycythemia disorder is commonly referred to as:

A patient diagnosed with myelofibrosis secondary to gastrointestinal disease may develop a __________ anemia due to excessive blood loss.