An unknown patient sample has many cells with differentiated blasts that contain cerebriform nuclei, prominent nucleoli, and abundant translucent cytoplasm.  Cytochemical stains were performed and the results are as follows:             MPO: Weakly positive     SBB: Weakly positive                 NSE: Positive           SE: Negative  Cytogenetics detected 11q23 on the karyotype for this patient.               What is the most probable diagnosis?

What is the largest challenge when using RNA for molecular testing?

Which statement about hematologic malignancies is correct?

Which of the following is an expected finding in ET?

Which of the following cell lines lack expression of CD45?

The identity of a granulocyte is determined by the __________ and they appear at the ____________ stage of development.  

Which of the following genetic mutations is associated with a worse prognosis of Acute Lymphoblastic Leukemia or chronic myelogenous leukemia? 

The process of antigen recognition for neutrophils is achieved by: 

Choose the chromosome number from the choices below that represents a cytogenetic polyploidy. 

A patient’s peripheral blood sample has a dimorphic population, many oval macrocytes,  neutrophils with persistent basophilic cytoplasm, and giant agranulated platelets.  What two lab tests would you order to confirm these findings?