A paediatric patient who weighs 20.8 kg, has been newly diagnosed with epilepsy and is prescribed phenytoin 2.5 mg/kg daily. What is the volume in millilitres of phenytoin 30 mg/5 mL suspension that the patient should receive per dose? Give your answer to ONE (1) decimal place.  

85. The belief that the reward you receive will depend on your performance in the workplace. 

You receive the following prescription for a six-year-old child for prophylaxis of a urinary tract infection with oral nitrofurantoin 25 mg/5 mL suspension.    What dose in millilitres should the child be given each evening? Give your answer to ONE (1) decimal place.

You are working as a pharmacist independent prescriber within primary care. A patient is diagnosed with vitamin D deficiency following a recent serum 25-hydroxyvitamin D result of 13 nmol/L. You decide to prescribe Fultium-D3 (colecalciferol) 20,000 iu capsules, TWO to be taken WEEKLY for 7 weeks. What is the total dose of colecalciferol in milligrams that the patient will receive over the course of treatment?   International unit = iu 1000 iu = 25 mcg

56.   You made a 1:1000 dilution of your culture, and plated 0.1 ml of this sample on               a Nutrient agar plate.  After incubation, you counted 50 colonies on the                           plate. How many organisms were in the original culture?            

a. Briefly describe the Vaughan Williams classification scheme for antiarrhythmic drugs. Name ONE representative drug for each class.  (4 marks) b. Drugs belonging to which TWO of the named classes are currently recommended for long-term rate control in patients with atrial fibrillation?  (1 mark)

Discuss the medicinal chemistry behind the design of the typical antipsychotics, and rationalise the specific side-effects associated with this class of drug. (5 Marks)

A 60 year old male, has a long history of bipolar disorder and recently he has been diagnosed with angina. Before he started treatment with lithium he had frequent episodes of suicidal depression. Equally problematic were episodes of hypomania, which proved to be destructive to his family life and job.   a. Explain in detail the mechanism of action of lithium on bipolar disorder?                                                                                                                                                                                            (2 Marks)   b. List the minor /reversible side effects of lithium on gastrointestinal, cardiovascular, renal and central nervous system (including neuromuscular) in the presence of a steady state plasma concentration (0.4 – 1 mmol/L)                                                                                                                                                                                  (3 Marks)

75. Gender barriers are one of the causes why there’s an underrepresentation of women in (STEM). 

EP, a 70-year-old patient with a history of coronary artery disease, has been prescribed simvastatin 40 mg daily. He has come to your community pharmacy, and says that his neighbour told him that he was unable to drink a particular kind of fruit juice with his statin, but he can’t remember what they said. Which ONE of the following would you advise EP to avoid?