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A 15-year-old boy presents complaining of severe headaches;…

A 15-year-old boy presents complaining of severe headaches; he has a white count of 76.0 x 109/L, platelet count of 55 x 109/L, and a hematocrit of 33%. When a white cell differential is performed, most of the nucleated cells are blasts. They are CD2, CD4, and CD8 positive. What is the most likely condition? 

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Which nonmalignant alteration is associated with poor mucopo…

Which nonmalignant alteration is associated with poor mucopolysaccharide processing and can be easily confused with toxic granulation? 

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Cell dysfunction in the myelodysplastic syndromes may be pre…

Cell dysfunction in the myelodysplastic syndromes may be present in:

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An unknown patient sample has many cells with differentiated…

An unknown patient sample has many cells with differentiated blasts that contain cerebriform nuclei, prominent nucleoli, and abundant translucent cytoplasm.  Cytochemical stains were performed and the results are as follows:             MPO: Weakly positive     SBB: Weakly positive                 NSE: Positive           SE: Negative  Cytogenetics detected 11q23 on the karyotype for this patient.               What is the most probable diagnosis?

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What is the largest challenge when using RNA for molecular t…

What is the largest challenge when using RNA for molecular testing?

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Which statement about hematologic malignancies is correct?

Which statement about hematologic malignancies is correct?

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Which of the following is an expected finding in ET?

Which of the following is an expected finding in ET?

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Which of the following cell lines lack expression of CD45?

Which of the following cell lines lack expression of CD45?

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The identity of a granulocyte is determined by the _________…

The identity of a granulocyte is determined by the __________ and they appear at the ____________ stage of development.  

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Which of the following genetic mutations is associated with…

Which of the following genetic mutations is associated with a worse prognosis of Acute Lymphoblastic Leukemia or chronic myelogenous leukemia? 

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