Bradykinesia has made drug treatment necessary in a 60-year-old man with Parkinson’s disease. The plan is to initiate levodopa. Which of the following statements would NOT be appropriate to advise the patient with regards to levodopa therapy?
Read DetailsA 25-year-old man with idiopathic generalized epilepsy with generalized tonic-clonic seizures, continues to have breakthrough seizures despite being on maximally tolerated doses of lamotrigine. Sodium valproate is added to his treatment regimen. Which of the following effects may result from interaction between these drugs?
Read DetailsMrs AB is a 56-year-old patient who has a history of epilepsy. She has been poorly controlled recently and her neurologist has initiated her on phenytoin. She was initially prescribed a dose of 300mg daily, however her dose has recently been increased to 350mg daily. Shortly following this dose increase she began to experience symptoms of phenytoin toxicity. Explain why small dose increments with phenytoin can result in toxicity? (5 Marks)
Read DetailsA 28-year-old woman with known anxiety presents to her GP. She is due to give a presentation at work to an important crowd of people and is worried about sweating, flushing and shaking in public and has asked for some medication. She is not known to have any medical history and has no drug allergies. Which of the following can provide the MOST appropriate symptomatic control of her performance related anxiety?
Read DetailsA 27-year-old woman has recently been diagnosed with schizophrenia. She is due to start antipsychotic therapy and a range of baseline investigations have been requested. Which of the following investigations is NOT routinely recommended before initiation of antipsychotic therapy?
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