What destroys the red cells in paroxysmal nocturnal hemoglobinuria?

Which of the following sets of data follows the rule of three? (Objective 3) Choice RBC Hgb Hct A 4.50 x 10^6/ul 11.0 g/dl 43% B 4.50 x 10^6/ul 13.5 g/dl 40.5% C 3.00 x 10^6/ul 12.0 g/dl 36% D 3.25 x 10^6/ul 11.5 g/dl 34.5%

A man and woman are expecting a child next month.  The soon-to-be mom has sickle cell trait and the soon-to-be dad has sickle cell disease (phenotype SS).  What is the probability that the child produced will have the sickle cell trait? 

A patient waiting for a liver transplant is admitted to the local hospital.  Initial admission labs are drawn which show an MCHC of 41%.  A manual hematocrit is spun and the supernatant is green.  What is the erroneous CBC parameter and what would you do to correct it? 

Interpret the gel below.  What is the most likely patient population in lane 6?   

Refer to the chart below.  What is the most likely diagnosis associated with the values in Choice B? (Objective 10) Choice RBC Hgb Hct A 1.50 x 10^6/ul 6.5g/dl 18.3% B 4.50 x 10^6/ul 10.1 g/dl 30.2% C 3.00 x 10^6/ul 9.0 g/dl 27% D 3.25 x 10^6/ul 11.5 g/dl 34.5%

In Beta thalassemia, other globin chains combine with alpha chains to compensate for the decrease in the Beta chain production.  This increase is seen in an adult on electrophoresis as: 

G-6-PD deficiency usually does not cause a problem for a patient except when: 

Which result is typical in stage 3 iron deficiency anemia?

An African-American patient comes to the emergency room with complaints of shortness of breath, abdominal pain and joint pain. The physician orders a CBC and solubility test.  The results are:   Test Value Reference Range WBC 10 x 103/ul 3.5-11.0 x 103/ul RBC 2.59 x 106/ul 3.5-5.5 x 106/ul HGB 7.8 g/dl 13.0-17.0 g/dl HCT 22.8% 40-50% MCV 88 fl 80-100 fl MCH 30.1 pg 27-31 pg MCHC 34.2% 32-36% RDW 20.8