This is the beginning of the short answer portion of the exa…
This is the beginning of the short answer portion of the exam Assume the pink rectangles below represents a basal layer of epithelial cells. Based on this diagram indicate Which adhesive junctions would be found in 8 (2 points) Two of the main components of this structures (of structure A) (2 points) The name of the structure represented in B (2 points) Two of its main components (of structure B) (2 points)
Read DetailsChanges in the ability of cells to adhere to other cells or…
Changes in the ability of cells to adhere to other cells or to the extracellular matrix (ECM) have been implicated in promoting metastasis. Describe 2 properties that we have covered in class that can specifically make an epithelial cell more metastatic.
Read DetailsBonus question: When integrin-ECM adhesion is lost, cells di…
Bonus question: When integrin-ECM adhesion is lost, cells die via detachment-induced apoptosis. If you culture isolated liver cells (hepatocytes) and add RGD peptides, would you expect them to survive? Why or why not? Explain your answer (5 points)
Read DetailsEpidermolysis bullosa is a group of rare medical conditions…
Epidermolysis bullosa is a group of rare medical conditions that cause fragile, blistering skin. Patients with the disease have genetic alterations in one or multiple proteins involved in the formation of the adhesive structures called hemidesomosomes. These include: (select all that apply)
Read Details