67.  Which of these statements is FALSE?        

A 54-year-old male patient is admitted to hospital with a complicated skin and soft tissue infection (cSSTI), identified as being caused by staphylococcus aureus bacteraemia (SAB). He is prescribed daptomycin and you check his kidney function before recommending a dose. His weight is 72 kg and serum creatinine is 190 micromol/litre.   What would be the most appropriate dose of daptomycin to prescribe daily for this patient? Give your answer in milligrams.        Constant: 1.04 (women) 1.23 (men)   Extract from the SPC for daptomycin

61.   You inoculated two tubes of liquid culture media with 100 bacterial cells, and                  incubated one tube at 37oC and the other at 55oC.  After 48 hours incubation,                you  Counted 20,000 bacteria per ml in the 37oC tube and 1,000, 000 bacteria per ml in the 55oC tube.  You can conclude that this species is a:            

A paediatric patient who weighs 20.8 kg, has been newly diagnosed with epilepsy and is prescribed phenytoin 2.5 mg/kg daily. What is the volume in millilitres of phenytoin 30 mg/5 mL suspension that the patient should receive per dose? Give your answer to ONE (1) decimal place.  

85. The belief that the reward you receive will depend on your performance in the workplace. 

You receive the following prescription for a six-year-old child for prophylaxis of a urinary tract infection with oral nitrofurantoin 25 mg/5 mL suspension.    What dose in millilitres should the child be given each evening? Give your answer to ONE (1) decimal place.

You are working as a pharmacist independent prescriber within primary care. A patient is diagnosed with vitamin D deficiency following a recent serum 25-hydroxyvitamin D result of 13 nmol/L. You decide to prescribe Fultium-D3 (colecalciferol) 20,000 iu capsules, TWO to be taken WEEKLY for 7 weeks. What is the total dose of colecalciferol in milligrams that the patient will receive over the course of treatment?   International unit = iu 1000 iu = 25 mcg

56.   You made a 1:1000 dilution of your culture, and plated 0.1 ml of this sample on               a Nutrient agar plate.  After incubation, you counted 50 colonies on the                           plate. How many organisms were in the original culture?            

a. Briefly describe the Vaughan Williams classification scheme for antiarrhythmic drugs. Name ONE representative drug for each class.  (4 marks) b. Drugs belonging to which TWO of the named classes are currently recommended for long-term rate control in patients with atrial fibrillation?  (1 mark)

Discuss the medicinal chemistry behind the design of the typical antipsychotics, and rationalise the specific side-effects associated with this class of drug. (5 Marks)