An awake and alert female patient who is 5’6″ tall was just placed on the following weaning mode. Parameters are below: CPAP – 5 cm H2O Total rate – 16 breaths PSV – 10 cm H2O Tidal volume – 450 ml FIO2 – 45% RSBI – 40 MIP – (-35) What should be done next?

A physician would like to place her patient on SIMV after SBT. The following below is the patient’s current ventilator settings. What rate would you suggest beginning SIMV for weaning?   Mode – ACRate – 14 breaths/minVT – 450 mlPEEP – 5 cm H2OFIO2 – 0.30  

A patient on the following mode is showing some distress and his physician would like to start pressure support. What setting would be appropriate to start with based on the current information?   Mode – SIMV Total rate – 30 Rate – 8 PIP – 30 cm H2O Tidal volume – 450 ml Plateau – 20 cm H2O PEEP – 5 cm H2O FIO2 – 0.35  

When fostering the correct environment for innovation, one thing a manager should do is separate funds for innovation.

Normative institutions are concerned with:

The strategic process DOES NOT include which of the following steps?

Buyers gain power when the costs of switching to competing brands or substitutes are high.

What are endocytosis and exocytosis, and what are some (3) specific types of endocytosis?

What is the evidence supporting the endosymbiosis theory for the origin of mitochondria and chloroplasts?

OBJECTIVE GENETIC PATHOPHYSIOLOGY & INHERITANCE Which genetic pattern of inheritance is associated with hemophilia A and B? X-linked recessive Matching: Williams syndrome – arteriopathies, joint hypermobility, skin laxity, an “elfin-like” appearance, and a unique personality with overfriendliness and distinctive empathyAngelman syndrome – intellectual disability, developmental delay, seizures, and a distinctive happy demeanor with frequent smiling & inappropriate laughter; fair skin & light colored hair Prader-Willi syndrome – with hyperphagia, weight gain, and history of hypotonia and poor sucking in infancy Wiskott-Aldrich syndrome – severe eczema with microthrombocytopenia   Inversion – Chromosomal segment breaks off and reattaches within the same chromosome, but in reverse orientation Point mutation – A single base pair is added, deleted or changed. Translocation – Chromosome breaks and the fragmented pieces re-attach to different chromosomes Missense mutation – DNA change resulting in different amino acids being encoded at a particular position in the resulting protein   PCSK9 – Familial Hypercholesterolemia DMD – Duchenne muscular dystrophy APC – Familial adenomatous polyposis Factor VIII or factor XI – Hemophilia A 6-year-old boy who has intellectual disability secondary to fragile X syndrome has been admitted to hospital.  The NP knows what about the inheritability of the disease? The boy will pass the gene to all his future daughters who will become carriers. What is the risk for the recurrence of Marfan Syndrome? 50% What is the cause of familial hypercholesterolemia (FH)? Reduction in the number of low-density lipoprotein (LDL) receptors on cell surfaces The NP’s patient has Down Syndrome. The most common cause of this disorder is: nondisjunction during meoisis. A carrier of cystic fibrosis is an individual who carries and is capable of passing on genetic mutation associated with a disease and may or may not display disease symptoms (although I accepted 2 answers on this one — this one is the most correct)  The WHNP is seeing a pregnant patient, at 13 weeks gestation (G2, A0, P0, T1), with her second pregnancy. The patient is anxious because her first born child had spina bifida (a neural tube defect or NTD) and the patient expresses concern that her baby she is carrying will also have the condition.  The WHNP knows that that neural tube defects arise from a combination of genetic and environmental factors. Circles represent females; squares represent males. Normal individuals are white in color; affected individuals are represented by blue shading: What inheritance pattern does this pedigree represent? Autosomal dominant  Males are more often affected by which type of genetic disease?  Sex-linked recessive The PNP is seeing an infant in clinic – The infants has been struggling to gain weight (currently in the 5% percentile for weight), is suffering from constipation & rectal prolapse, and has had multiple respiratory infections in their short life. The PNP orders a sweat test looking for which electrolyte? Chloride (this questions assesses students ability to both identify the symptoms of the disease, then identify the patho/cause) Which of the following statements about the heritability of schizophrenia is true? Both genetic and epigenetic factors contribute to the heritability of schizophrenia.