In the disease Cystic Fibrosis (CF), a chloride channel (CFT…
In the disease Cystic Fibrosis (CF), a chloride channel (CFTR) is defective which results in reduced Cl− and water movement across the plasma membrane. In the lungs this is serious because mucus builds up leading to colonization by infectious bacteria. If you learn that the CFTR is a member of the family of ABC transporters, what might you conclude about the CFTR?
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