Willis and Leslie orally agree to the sale of a parcel of land for $50,000: one-half payable now as a down payment; one-half payable in 30 days at the time of closing when the title will be transferred. The buyer, Willis, is to have possession immediately. Willis pays Leslie $25,000, takes possession of the land, and starts building a house. At the time of closing, Willis has made a substantial beginning on the house. However, Leslie refuses to transfer the title, claiming the oral contract is not enforceable. This contract is:

Amy Hudson has been trying to purchase Glen Cappel’s antique desk for some time, but Glen has been reluctant to sell. One evening Glen said to Amy, “Okay, I’ll sell the desk for $550.” Amy replied, “Thank you, Glen. I accept.” The agreement was not reduced to writing, but Glen and Amy did shake hands. Two days later, Amy sent Glen a letter outlining the terms of the agreement, and stating that she would deliver $550 cash according to the agreement within ten days. The letter was signed, “Best regards, Amy.” Later, Amy had second thoughts, and refused to go through with the purchase. Nothing had been exchanged at this point. Glen:

A 34 year old female is diagnosed with bipolar 1 disorder is exhibiting severe manic behaviors. A PMHNP-BC prescribes lithium carbonate and olanzapine. The client’s spouse asks the PMHNP-BC how olanzapine works. Which is the appropriate nursing response

A 27-year-old male presents for evaluation after experiencing intense cravings and compulsive drug-seeking behavior following prolonged methamphetamine use. Neuroimaging studies suggest heightened dopaminergic activity in regions associated with reward and reinforcement.Which of the following brain structures is most directly involved in mediating the reinforcing effects of addictive substances through dopamine release?

Antidepressants have the poetential of causing sodium imbalance, RBC anbnormalities, and cardiac issues.

A 19-year-old college student is prescribed Risperidone for the treatment of First Episode Psychosis. After three weeks of adherence, the patient reports a complete cessation of auditory hallucinations but complains of a “total inability to feel joy,” decreased motivation, and a flat emotional response. The PMHNP recognizes that while the medication is effectively blocking D2 receptors in the mesolimbic pathway to treat positive symptoms, it may also be impacting the brain’s “reward center.”Which neurotransmitter and pathway are primarily responsible for these new-onset symptoms of secondary anhedonia?

A 32-year-old female with a diagnosis of Schizoaffective Disorder is being switched from Haloperidol to Olanzapine (Zyprexa). During the follow-up appointment four weeks later, the patient reports a 10-pound weight increase and complains that she is “sleeping 12 hours a day” and feels groggy throughout the morning. The PMHNP explains that these side effects are common with certain Second-Generation Antipsychotics (SGAs) due to their high affinity for specific off-target receptors.Antagonism of which receptor type is primarily associated with the side effects of weight gain and sedation?

A 42-year-old male is brought to the clinic for a psychiatric evaluation after his spouse noted a significant change in his personality. The patient, previously a detail-oriented engineer, has begun making impulsive financial decisions and struggles to organize complex tasks or grasp abstract concepts during the interview. Neurobiological dysfunction in which of the following brain regions is most likely responsible for these deficits in executive functioning and abstract reasoning?

A 34-year-old male is admitted for a psychiatric evaluation following a severe motor vehicle accident involving a head injury. During the admission, the PMHNP notes that the patient exhibits significant cognitive slowing and disorganized thinking. The patient is currently being treated with Memantine for cognitive symptoms and is also receiving Ketamine for treatment-resistant depression. Understanding that these medications both target the primary excitatory neurotransmitter system, which of the following neurotransmitters is most likely being modulated?

You are the PMHNP caring for a client who is a smoker with a lithium level of 1.7. As the PMHNP, you should look for signs and symptoms of lithium toxicity and consider reducing the dose of lithium as nicotine is known as an inducer.