Rearrangement of the α chain continues until: Rearrangement of the α chain continues until: Read Details
A naive T-cell binds to peptide:MHC II with its TCR and CD4… A naive T-cell binds to peptide:MHC II with its TCR and CD4 co-receptor, which other molecules need to interact in order for the T-cell to become activated? Read Details
What happens to thymocytes with unproductive TCR gene rearra… What happens to thymocytes with unproductive TCR gene rearrangements? Read Details
Which of the following cell-surface molecules would you expe… Which of the following cell-surface molecules would you expect to be expressed on the surface of an effector T-cell homing to the site of infection? Read Details
The pre-TCR complex is composed of a functional α chain, a s… The pre-TCR complex is composed of a functional α chain, a surrogate β chain (preTβ), CD3 proteins and ζ chain. Read Details
Cross presentation occurs when an MHC class I molecule prese… Cross presentation occurs when an MHC class I molecule presents _____ antigens to a CD8 T-cells. Read Details
What would be the result of a 35 year old male getting a thy… What would be the result of a 35 year old male getting a thymectomy? Read Details
The two most common lineages of T-cells, α:β and μ:δ T-cells… The two most common lineages of T-cells, α:β and μ:δ T-cells, develop in parallel from common precursors. Read Details
The pre-TCR complex is composed of a functional α chain, a s… The pre-TCR complex is composed of a functional α chain, a surrogate β chain (preTβ), CD3 proteins and ζ chain. Read Details
Upon recognition of pathogen via innate immune receptors, wh… Upon recognition of pathogen via innate immune receptors, what co-stimulatory molecule does a dendritic cell start expressing that allows it to activate naive T-cells? Read Details