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Positive selection:

Positive selection:

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Which of the following receptor genes are the first to be re…

Which of the following receptor genes are the first to be rearranged in a double negative thymocyte?

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T-cells go through somatic recombination in the ____________…

T-cells go through somatic recombination in the _____________, and T-cells differentiate into effector cells in the ___________.

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Which of the following can be found in the thymus?

Which of the following can be found in the thymus?

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Effector T cell homing to inflamed tissue is facilitated by…

Effector T cell homing to inflamed tissue is facilitated by _________ expression on the effector T cell surface.

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Both B-cells and T-cells have up to 4 potential attempts to…

Both B-cells and T-cells have up to 4 potential attempts to productively rearrange their heavy chain and β-chain genes respectively.

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Homing of a naive T cell into a lymph node is initially dete…

Homing of a naive T cell into a lymph node is initially determined by L-selectin binding to a/an:

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T-cells go through somatic recombination in the ____________…

T-cells go through somatic recombination in the _____________, and T-cells differentiate into effector cells in the ___________.

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Central tolerance for T cells takes place after activation i…

Central tolerance for T cells takes place after activation in the bone marrow.

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The expression of the pre-T-cell receptor is required in ord…

The expression of the pre-T-cell receptor is required in order to halt β-,γ-, and δ-chain rearrangements and induce proliferation of the thymocyte.

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