A 72-year-old woman with known HFrEF (LVEF 30%) presents to…
A 72-year-old woman with known HFrEF (LVEF 30%) presents to the emergency department with worsening dyspnea over 3 days. Examination reveals bibasilar crackles, jugular venous distension to 12 cm, and 2+ pitting edema to the knees bilaterally. Blood pressure is 142/88 mm Hg and oxygen saturation is 91% on room air. What is the primary therapeutic role of loop diuretics in this clinical setting?
Read DetailsA 64-year-old man with HFrEF (LVEF 32%) has been stable on l…
A 64-year-old man with HFrEF (LVEF 32%) has been stable on lisinopril 20 mg daily, carvedilol, spironolactone, and dapagliflozin. His blood pressure is 122/74 mm Hg, potassium is 4.6 mEq/L, and creatinine is 1.2 mg/dL. You plan to transition him from lisinopril to sacubitril/valsartan. What is the most important safety consideration when making this transition?
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