Identify the correct order for the three phases of the Inves…
Identify the correct order for the three phases of the Investigational New Drug (IND) process (1) define a safe and efficacious dose range using several hundred subjects with the disease or condition(2) demonstrate long-term safety and efficacy using expanded controlled & uncontrolled trial with “final” formulas (3) determine safe dose by small number (30 to 80) of healthy subjects using agent or product
Read DetailsCase #2 – Your patient is a 59-year-old male who presents to…
Case #2 – Your patient is a 59-year-old male who presents to have his “teeth cleaned”. He is of average height and visibly overweight. His medical history indicates the patient had an operation eight (8) years ago to repair a hiatal hernia, has diabetes that is “fairly well controlled” by diet and medication, has high blood pressure, and smokes 1 1/2 packs of cigarettes a day. Medications taken are Glucophage (oral med for diabetes), Lasix and Dyazide for high blood pressure. The patient stated he checked his blood sugars which were normal. The patient was late for the appointment but still had to wait on you and says he’s now “very upset”. He has not had his teeth cleaned in over 15 years and wants to “get this over with”.Question: Your patient suddenly turns pale and complains of dizziness, nausea, and intense pain in his left shoulder area and left arm. What should you do?
Read DetailsCase #1 – Your patient is new to your practice. He is a 46 y…
Case #1 – Your patient is new to your practice. He is a 46 year old white male of average height and weight. He indicates on the health history that he has sinus problems due to allergies and had a knee replacement done 10 years ago in another state after chronic issues related to a football injury. He has a history of irregular dental care, and has not had his teeth cleaned “in a few years”, explaining that he had a prosthetic joint infection in his knee seven (7) years ago after having a dental procedure done. He is concerned about it happening again and is”just one of the reasons” he has avoided keeping up with regular dental care. His vital signs are pulse 88, respirations 20, and blood pressure 156 / 86. He says he is noticing bleeding of his gums when he brushes, but tries “not to brush too hard so it doesn’t happen”. He has a three unit bridge in the UR anterior area involving #6, 7, 8 and several other amalgam and composite restorations. There is an obvious cavitated lesion adjacent to an amalgam filling on #3 occlusal.Question: Which of the following would not be helpful in cleaning underneath the three unit fixed bridge?
Read DetailsCase #2 – Your patient is a 59-year-old male who presents to…
Case #2 – Your patient is a 59-year-old male who presents to have his “teeth cleaned”. He is of average height and visibly overweight. His medical history indicates the patient had an operation eight (8) years ago to repair a hiatal hernia, has diabetes that is “fairly well controlled” by diet and medication, has high blood pressure, and smokes 1 1/2 packs of cigarettes a day. Medications taken are Glucophage (oral med for diabetes), Lasix and Dyazide for high blood pressure. The patient stated he checked his blood sugars which were normal. The patient was late for the appointment but still had to wait on you and says he’s now “very upset”. He has not had his teeth cleaned in over 15 years and wants to “get this over with”. Question: You complete the Tobacco / Other Use Assessment form with your patient and he states he is “Not at all” interested in stopping his use. What should you do next?
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