Phenotypic Expression = Genotype +

Whole blood sample after centrifuged. List the visible layers of separation.  Select all choices that applied.

(20 pts.)  Show the mechanism for following reaction. YOU ARE REQUIRED TO SHOW THE GENERATION OF THE ELECTROPHILE IN THIS REACTION (it is NO2+) from the reagent. You will need to show the resonance contributors for the sigma complex. Each organic structure needs to be drawn in LINE ANGLE.

A patient presents with bleeding and poor wound healing. PT, PTT, fibrinogen, and platelet count are all normal. Which assay would be most appropriate?

A prolonged PT with normal PTT and TT is most suggestive of deficiency of:

A patient with recurrent thrombosis has a prolonged PTT but no history of bleeding. The mixing study fails to correct. Which condition is most likely?

What was the principle behind the original Lee-White coagulation test?

A patient has a prolonged PT of 24 seconds with normal PTT and TT results. Which coagulation factor deficiency is most likely?

The major reagent component that initiates coagulation in the PT assay is:

Dilute Russell viper venom time (dRVVT) is routinely used to detect: