Let X be the number of material anomalies occurring in a par…
Let X be the number of material anomalies occurring in a particular region of an aircraft gas-turbine disk. The article “Methodology for Probabilistic Life Prediction of Multiple-Anomaly Materials” (Amer. Inst. of Aeronautics and Astronautics J., 2006: 787–793) proposes a Poisson distribution for X. Suppose that the mean number of anomalies of a gas-turbine disk is 4. a. What is the probability that at most 6 anomalies are discovered on a single disk? b. What is the probability that between 3 and 9 anomalies are discovered on a single disk? c. What is the probability that the number of anomalies exceeds the mean number by no more than 2 deviations? d. If 2 disks are randomly selected, what is the probability that each disk would have at most one anomaly?
Read DetailsApproval of the Pfizer and Moderna COVID mRNA vaccines by th…
Approval of the Pfizer and Moderna COVID mRNA vaccines by the FDA required they be tested in formal clinical trials. Using the randomized controlled trials of the COVID mRNA vaccines as a case study example… Indicate the various phases of a clinical trial, and for each phase- describe the broader goal or objective of the phase, the approximate number of subjects expected to be enrolled, whether there is a placebo control, what a logical primary outcome would be, what a secondary outcome(s) might be, and how what gets measured in the subjects as outcomes would be expected to change/evolve through the phases. Assume the goal is to achieve FDA-approval for use in humans, and there was no prior experience with mRNA-based vaccines in this context.
Read Details