In the Human Microbiome Consortium paper the authors observe…
In the Human Microbiome Consortium paper the authors observed that, “although each individual’s saliva was ecologically rich, members of the population shared similar organisms” Answer the following questions regarding the provided figure and statement. Define alpha-diversity and indicate which part of the quoted statement is referring to alpha diversity. (two sentences maximum) Which part of Figure 1 provides evidence to support the conclusions presented in the quote? Choose Figure 1.a, 1.b, 1.c or 1.d. Define beta-diversity and indicate which part of the quoted statement is referring to beta diversity. (two sentences maximum) Which part of Figure 1 provides evidence to support the conclusions presented in the quote? Choose Figure 1.a, 1.b, 1.c or 1.d. Figure 1 | Diversity of the human microbiome is concordant among measures, unique to each individual, and strongly determined by microbial habitat. a, Alpha diversity within subjects by body habitat, grouped by area, as measured using the relative inverse Simpson index of genus-level phylotypes (cyan), 16S rRNA gene OTUs (blue), shotgun metagenomic reads matched to reference genomes (orange), functional modules (dark orange), and enzyme families (yellow). The mouth generally shows high within-subject diversity and the vagina low diversity, with other habitats intermediate; variation among individuals often exceeds variation among body habitats. b, Bray–Curtis beta diversity among subjects by body habitat, colours as for a. Skin differs most between subjects, with oral habitats and vaginal genera more stable. Although alpha- and beta-diversity are not directly comparable, changes in structure among communities (a) occupy a wider dynamic range than do changes within communities among individuals (b). c, Principal coordinates plot showing variation among samples demonstrates that primary clustering is by body area, with the oral, gastrointestinal, skin and urogenital habitats separate; the nares habitat bridges oral and skin habitats. d, Repeated samples from the same subject (blue) are more similar than microbiomes from different subjects (red). Technical replicates (grey) are in turn more similar; these patterns are consistent for all body habitats and for both phylogenetic and metabolic community composition. See previously described sample counts1 for all comparisons.
Read DetailsA patient with HIV who is taking zidovudine reports increasi…
A patient with HIV who is taking zidovudine reports increasing fatigue, persistent nausea, abdominal discomfort, and shortness of breath. The nurse notes the patient is tachypneic. Laboratory results show elevated liver enzymes. Which complication should the nurse suspect?
Read DetailsA 72-year-old male is admitted with sepsis secondary to a pe…
A 72-year-old male is admitted with sepsis secondary to a perforated bowel. He has a history of chronic kidney disease (CKD stage 3) and a seizure disorder controlled with levetiracetam (keppra). The provider prescribes Imipenem IV. Current labs: Creatinine: 2.5 mg/dL (normal range 0.7–1.3 mg/dL) BUN: 38 mg/dL (normal range 7–20 mg/dL) Potassium: 4.6 mEq/L (Normal range 3.5-5 mEq/L) WBC: 18,000/mm³ (Normal range 4.0–11.0 × 10³/µL) Temperature: 102.4°F (39.1°C) Which assessment finding requires the nurse’s immediate follow-up?
Read DetailsSamples were taken from multiple skin locations and grouped…
Samples were taken from multiple skin locations and grouped based on a single shared environmental characteristic. Based on the microbiota present in the samples identify the general skin characteristic for each environment. Note, you do NOT need to provide specific locations (like scalp, forearm, etc.). Environment 1: [a] Environment 2: [b] Environment 3: [c]
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