You have been asked to conduct a medication review for a 78-year-old man. PMH: Mild Alzheimer’s disease, depression, insomnia Medications: Donepezil 10mg daily (started 6 months ago) Temazepam 20mg at night (started 20 years ago) Amitriptyline 75mg twice daily (started 10 years ago)   Outline any changes you would suggest as a result of your medication review and provide full justification for your suggestions. (5 Marks)

Which of the following anxiolytic drugs would be MOST appropriate? The serotonin system is involved in many processes in psychiatry including, most prominently mood, sleep and psychosis. In which of the following structure is serotonin primarily synthesised?  

A 20-year-old male has been prescribed fluoxetine by his GP for newly diagnosed depression. He has no significant past medical history other than a recent femur fracture (sporting accident). Drug history: Tramadol 50mg QDS PRN, Paracetamol 1g QDS, occasional use of recreational drugs. What would be the MOST appropriate course of action in relation to his prescription?

Which of the following would be an example of biological contamination?

What type of loading occurs when a muscle/ tendon/ ligament is stretched or lengthened?

A 68-year-old man with chronic renal failure is referred for peritoneal dialysis. Which of the following is the most likely complication of this form of dialysis?

PC was diagnosed with congestive heart failure 6 months ago. She has been stabilised on furosemide 40 mg OD, lisinopril 10 mg OD and bisoprolol 5 mg OD, but she is still symptomatic. According to current NICE guidance, which of the following drugs or drug combinations should be considered next as add-on therapy for PC?  

A 55-year-old male has been prescribed Nitroglycerin transdermal patches (Deponit®) for his angina. Which of the following statements is CORRECT with regards to these patches?

In the central nervous there are a number of neurotransmitters which are either excitatory or inhibitory in their actions. Which one of the following is the MAJOR excitatory neurotransmitter in the brain?

A person applies 665 N of force to the ground and they have a vertical displacement of 1.3 m.  They apply this force over a time period of 0.8 s.  What is their power output? ENTER YOUR ANSWER WITHOUT UNITS. ROUND YOUR ANSWER TO TWO SIGNIFICANT FIGURES (Ex: 2.56, 5.32)