The mutation that causes factor V Leiden causes a single ami…
The mutation that causes factor V Leiden causes a single amino acid substation from arginine to glutamine, which are similar in size and charge. The mutation does not cause an alteration in the structure or function of factor V in terms of promoting coagulation, but the mutation makes factor V produced from the mutated allele non-responsive to protein C/S. Which of the following correctly describes the nature of the mutation on the protein produced from the mutant allele?
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