Anti-K was detected in a patient’s serum 1 year ago in a routine antibody screen. This patient was transfused red cells containing antigen specific for anti-K. Forty-eight hours later the patient began exhibiting signs of a hemolytic anemia. What type of transfusion reaction is present?

What can cause extracorpuscular hemolytic anemia?

Although sickle cell trait is usually asymptomatic, sickling can still occur when caused by which of the following?

ADVANCED CONCEPTS A patient who usually takes metformin was switched to insulin immediately following an angiogram. Which patient finding indicates it is safe for the patient to switch back to metformin?

Where does extravascular phagocytosis of red cells occur?

The morphologic hallmark of HS hereditary spherocytosis on the peripheral blood smear is:

A 5-year-old boy presents with a hemoglobin and hematocrit of 10 g/dL and 30% respectively, a serum bilirubin of 3.0 mg/dL, a RBC count of 4.0 million/µL, and splenomegaly. Which clinical expression of thalassemia best correlates with the data?

ADVANCED CONCEPTSA patient is prescribed the testosterone patch 4 mg/day applied to the upper body once daily at night. Which side effects will you teach the patient may occur?

ADVANCED CONCEPTS A patient taking tamsulosin (Flomax) asks how the drug works. What is your best response?

Intravascular hemolysis due to mechanical etiologies is usually accompanied by the presence of __________ on the peripheral blood smear.