Order: Cefotaxime 750mg, intravenously, every 6 hours, for infection Child’s weight: 10 kg Safe dose range: 25-50 mg/kg/dose every 6 hours   a) What is the safe low dose (mg/dose) for this child? b) What is the safe high dose (mg/dose) for this child?  c) Is the ordered dose safe for this child?

Order: Amoxicillin 200mg, gastrostomy tube, twice daily, for acute otitis media  Supply: 125mg/5ml    a) How many milliliters (ml) will be administered to this child for each dose? 

Order: Diphenhydramine 30mg, oral, every 6 hours, for pruritus   Child’s weight: 66 lbs  Safe dose: 1mg/kg/dose every 6 hours, not to exceed 300mg/day     a) What is the safe dose (mg/dose) for this child?  b) Is the ordered dose safe for this child? 

Order: Morphine 0.55mg, intravenously, every 4 hours, for pain  Patient’s weight: 7.25 kg  Safe dose range:  0.05-0.1 mg/kg/dose every 4 hours    a) What is the safe low dose (mg/dose) for this child? Round to nearest hundredth.  b) What is the safe high dose (mg/dose) for this child? Round to nearest hundredth.  c) Is the ordered dose safe for this child? 

In an experiment pH measurements were made on three different soil types Alluvium (5 observation) Glacial Till (9 observations) Residuum (12 observations) If a Tukey pairwise comparison is to made the q critical is to be used.  What is the first degree of freedom, i.e. q([df1],df2)

A completely randomized design (CRD) is just another form of regression with 1 qualitative predictor

For performing Bonferroni’s simultaneous (pairwise) intervals with an experiment wise error rate of 10%, what should be the individual error rate for comparing 3 treatment groups to (only) the (fourth) control group?  That is, not all pairwise comparisons are to be made but a specific number, 1vs4, 2vs4, 3vs4

In a RCBD with 4 treatment levels and 5 block levels, what will the degrees of freedom for the error/residual term be?

In a Randomized Complete Block Design (RCBD), if the block factor is statistically significant, then the Relative Efficiency (RE) of the RCBD to a Completely Randomized Design (CRD) is most likely going to be

If the assumption of normality does not hold, in order to perform the classical inference on a RCBD, then one can use which distribution free method