Brain MRI shows a well-circumscribed “popcorn” lesion with a hemosiderin rim and prominent susceptibility (blooming) on T2*/SWI sequences; angiography may be normal. Most consistent with:

Which of the following pathologic findings is most characteristic of Parkinson disease?

A farmworker exposed to organophosphate insecticides presents with miosis, bronchorrhea/wheezing, bradycardia, salivation, lacrimation, vomiting, and diarrhea. This constellation represents:

A resident on call for a week has hyperglycemia, central adiposity over time, and delayed wound healing. Which stress-axis hormone is the primary mediator?

Ventricular remodeling after MI is driven in part by which mediator(s)?

A 29-year-old with 7 weeks of amenorrhea, unilateral pelvic pain, and spotting has β-hCG of 4,200 mIU/mL. Transvaginal ultrasound shows no intrauterine gestational sac. Best interpretation?

A patient reports persistent, excessive worry about work and family for over 6 months, with restlessness and sleep disturbance. This presentation is most consistent with:

A 55-year-old with progressive proximal muscle weakness has violaceous periorbital discoloration and erythematous papules over the MCPs. Which is most likely?

A 19-year-old with a peanut allergy develops hypotension, wheezing, and urticaria within minutes of ingestion. Which mechanism explains this response?

A 66-year-old with slowly progressive hyperthyroid symptoms has a nodular thyroid on exam; there is no ophthalmopathy or pretibial myxedema. Most likely etiology?